International Journal of Obstetric Anesthesia
Volume 15, Issue 1 , Pages 38-40 , January 2006

No place for racemic bupivacaine

    Proposer:
  • Marc Van de Velde

      Affiliations

    • Corresponding Author InformationM. Van de Velde MD, PhD, Director Obstetric Anesthesia and extra Muros Anesthesia, Department of Anesthesiology, University Hospitals Gasthuisberg, Herestraat 49, B - 3000 Leuven, Belgium. Tel.: +0032 16 34 42 70; fax: +0032 16 34 42 45.

References 

  1. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology. 1979;51:285–287
  2. Groban L, Dolinski SY. Differences in cardiac toxicity among ropivacaine, levobupivacaine, bupivacaine, and lidocaine. Techn Reg Anesth Pain Management. 2001;5:48–55
  3. Stienstra R. Ropivacaine for obstetric use. Techn Reg Anesth Pain Management. 2001;5:60–63
  4. Mather LE, Chang DHT. Cardiotoxicity with modern local anaesthetics. Is there a safer choice?. Drugs. 2001;61:333–342
  5. Santos AC, Arthur GR, Wlody D, De Armas P, Morishima HO, Finster M. Comparative systemic toxicity of ropivacaine and bupivacaine in nonpregnant and pregnant ewes. Anesthesiology. 1995;82:734–740
  6. Alahuhta S, Rasanen J, Jouppila P, et al. The effects of epidural ropivacaine and bupivacaine for Cesarean section on uteroplacental and fetal circulation. Anesthesiology. 1995;83:23–32
  7. Datta S, Camann W, Bader A, Vanderburgh L. Clinical effects and maternal and fetal plasma concentrations of epidural ropivacaine versus bupivacaine for Cesarean section. Anesthesiology. 1995;82:1346–1352
  8. Ala-Kokko TI, Alahuhta S, Jouppila P, Korpi K, Westerling P, Vahakangas K. Feto-maternal distribution of ropivacaine and bupivacaine after epidural administration for cesarean section. Int J Obstet Anesth. 1997;6:147–152
  9. Bader AM, Tsen LC, Camann WR, Nephew E, Datta S. Clinical effects and maternal and fetal plasma concentrations of 0.5% epidural levobupivacaine versus bupivacaine for Cesarean delivery. Anesthesiology. 1999;90:1596–1601
  10. Crosby E, Sandler A, Finucane B, et al. Comparison of epidural anaesthesia with ropivacaine 0.5% and bupivacaine 0.5% for Caesarean section. Can J Anaesth. 1998;45:1066–1071
  11. Griffin RP, Reynolds F. Extradural anaesthesia for Caesarean section: a double-blind comparison of 0.5% ropivacaine with 0.5% bupivacaine. Br J Anaesth. 1995;74:512–516
  12. Faccenda KA, Simpson AM, Henderson DJ, Smith D, McGrady EM, Morrison LMM. A comparison of levobupivacaine 0.5% and racemic bupivacaine 0.5% for extradural anesthesia for caesarean section. Reg Anesth Pain Med. 2003;28:394–400
  13. Chung CJ, Choi SR, Teo KH, Park HS, Lee SI, Chin YJ. Hyperbaric spinal ropivacaine for Cesarean delivery: a comparison to hyperbaric bupivacaine. Anesth Analg. 2001;93:157–161
  14. Gautier P, De Kock M, Huberty L, Demir T, Izydorczic M, Vanderick B. Comparison of the effects of intrathecal ropivacaine, levobupivacaine, and bupivacaine for Caesarean section. Br J Anaesth. 2003;91:684–689
  15. Danelli G, Fanelli G, Berti M, et al. Spinal ropivacaine or bupivacaine for cesarean delivery: a prospective, randomized, double-blind comparison. Reg Anesth Pain Med. 2004;29:221–226
  16. Ogun CO, Kirgiz EN, Duman A, Okesli S, Akyurek C. Comparison of intrathecal isobaric bupivacaine-morphine and ropivacaine-morphine for Caesarean delivery. Br J Anaesth. 2003;90:659–664
  17. Writer WDR, Stienstra R, Eddleston JM, et al. Neonatal outcome and mode of delivery after epidural analgesia for labour with ropivacaine and bupivacaine: a prospective meta-analysis. Brit J Anaesth. 1998;81:713–717
  18. Asik I, Goktug A, Gulay I, Alkis N, Uysalel A. Comparison of bupivacaine 0.2% and ropivacaine 0.2% combined with fentanyl for epidural analgesia during labour. Eur J Anaesthesiol. 2002;19:263–270
  19. Comparative Obstetric Mobile Epidural Trial (COMET) Study Group UK. Effect of low dose mobile versus traditional epidural techniques on mode of delivery: a randomised controlled trial. Lancet 2001; 358: 19–23.
  20. Halpern SH, Walsh V. Epidural ropivacaine versus bupivacaine for labor: a meta-analysis. Anesth Analg. 2003;96:1473–1479
  21. Campbell DC, Zwack RM, Crone LA, Yip RW. Ambulatory labor epidural analgesia: bupivacaine versus ropivacaine. Anesth Analg. 2000;90:1384–1389
  22. Meister GC, D’Angelo R, Owen M, Nelson KE, Gaver R. A comparison of epidural analgesia with 0.125% ropivacaine with fentanyl versus 0.125% bupivacaine with fentanyl during labor. Anesth Analg. 2000;90:632–637
  23. Gautier P, De Kock M, Van Steenberge A, Miclot D, Fanard L, Hody JL. A double blind comparison of 0.125% ropivacaine with sufentanil and 0.125% bupivacaine with sufentanil for epidural labor analgesia. Anesthesiology. 1999;90:772–778
  24. Lee BB, Ngan Kee WD, Ng FF, Lau TK, Wong ELY. Epidural infusions of ropivacaine and bupivacaine for labor analgesia: a randomized, double blind study of obstetric outcome. Anesth Analg. 2004;98:1145–1152
  25. Owen MD, Thomas JA, Smith T, Harris LC, D’Angelo R. Ropivacaine 0.075% and bupivacaine 0.075% with fentanyl 2 μg/ml are equivalent for labor epidural analgesia. Anesth Analg. 2002;94:179–183
  26. Gogarten W, Van de Velde M, Soetens F, et al. A multicentre trial comparing different concentrations of ropivacaine plus sufentanil with bupivacaine plus sufentanil for patient controlled epidural analgesia in labour. Eur J Anaesthesiol. 2004;21:38–45
  27. Chua NP, Sia AT, Ocampo CE. Parturient controlled epidural analgesia during labour: bupivacaine vs ropivacaine. Anaesthesia. 2001;56:1169–1173
  28. Fischer C, Blanie P, Jaouen E, Vayssiere C, Kaloul I, Coltat JC. Ropivacaine 0.1% plus sufentanil 0.5 μg/ml versus bupivacaine 0.1% plus sufentanil 0.5 μg/ml using patient controlled epidural analgesia for labor. Anesthesiology. 2000;92:1588–1593
  29. Lacassie HJ, Columb MO, Lacassie HP, Lantadilla RA. The relative motor blocking potencies of epidural bupivacaine and ropivacaine in labor. Anesth Analg. 2002;95:204–208
  30. Levin A, Datta S, Camann WR. Intrathecal ropivacaine for labor analgesia: a comparison with bupivacaine. Anesth Analg. 1998;87:624–627
  31. Hughes D, Hill D, Fee JPH. Intrathecal ropivacaine or bupivacaine with fentanyl for labour. Br J Anaesth. 2001;87:733–737
  32. Lim Y, Ocampo CE, Sia AT. A comparison of duration of analgesia of intrathecal 2.5 mg of bupivacaine, ropivacaine, and levobupivacaine in combined spinal epidural analgesia for patients in labor. Anesth Analg. 2004;98:235–239
  33. Lacassie HJ, Columb MO. The relative motor blocking potencies of bupivacaine and levobupivacaine in labor. Anesth Analg. 2003;97:1509–1513
  34. Vercauteren MP, Hans G, De Decker K, Adriaensen HA. Levobupivacaine combined with sufentanil and epinephrine for intrathecal labor analgesia: a comparison with racemic bupivacaine. Anesth Analg. 2001;93:996–1000
  35. Capogna G, Celleno D, Fusco P, Lyons G, Columb M. Relative potencies of bupivacaine and ropivacaine for analgesia in labour. Br J Anaesth. 1999;82:371–373
  36. Polley LS, Columb MO, Naughton NN, Wagner DS, van de Ven CJM. Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labour. Anesthesiology. 1999;90:944–950
  37. Polley LS, Columb MO, Naughton NN, Wagner DS, Van de Ven CJM, Goralski KH. Relative analgesic potencies of levobupivacaine and ropivacaine for epidural analgesia in labor. Anesthesiology. 2003;99:1354–1358
  38. Duggan J, Bowler GMR, McClure JH, Wildsmith JAW. Extradural block with bupivacaine: influence of dose, volume, concentration and patient characteristics. Br J Anaesth. 1988;61:324–331

PII: S0959-289X(05)00099-3

doi: 10.1016/j.ijoa.2005.06.006

International Journal of Obstetric Anesthesia
Volume 15, Issue 1 , Pages 38-40 , January 2006

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