International Journal of Obstetric Anesthesia
Volume 15, Issue 1 , Pages 41-43 , January 2006

There is no place in modern obstetrics for racemic bupivacaine

    Opposer
  • Martin Dresner

      Affiliations

    • Corresponding Author InformationMartin Dresner, Opposer, Department of Anaesthesia, Leeds General Infirmary, Leeds, UK.

References 

  1. Bardsley H, Gristwood R, Baker H, Watson N, Nimmo W. A comparison of the cardiovascular effects of levobupivacaine and racemic bupivacaine following intravenous administration to healthy volunteers. Br J Clin Pharmacol. 1998;46:245–249
  2. Jones M, Dresner M. Long term audit of satisfaction with epidural analgesia. Int J Obstet Anesth. 2002;11(Suppl):31
  3. Rolan P. A Two-Phase, Double-Blind, Three-Way Crossover Study to Compare the Effects of Racemic Bupivacaine and Levobupivacaine on the Spectral Components of the EEG. Study number ME0400/NX007. Cambridge, UK: Chiroscience.
  4. Lyons G, Columb M, Wilson RC, Johnson RV. Epidural pain relief: potencies of levobupivacaine and racemic bupivacaine. Br J Anaesth. 1998;81:899–901
  5. Camorcia M, Capogna G, Columb MO. Minimum local analgesic doses of ropivacaine, levobupivacaine, and bupivacaine for intrathecal labor analgesia. Anesthesiology. 2005;102:646–650
  6. Lacassie HJ, Columb MO. The relative motor blocking potencies of bupivacaine and levobupivacaine in labor. Anesth Analg. 2003;97:1509–1513
  7. Purdie NL, McGrady EM. Comparison of patient-controlled epidural bolus administration of 0.1% ropivacaine and 0.1% levobupivacaine, both with 0.0002% fentanyl, for analgesia during labour. Anaesthesia. 2004;59:133–137
  8. Benhamou D, Ghosh C, Mercier FJ. A randomized sequential allocation study to determine the minimum effective analgesic concentration of levobupivacaine and ropivacaine in patients receiving epidural analgesia for labor. Anesthesiology. 2003;99:1383–1386
  9. Michels AM, Lyons G, Hopkins PM. Lignocaine test dose to detect intravenous injection. Anaesthesia. 1995;50:211–213

PII: S0959-289X(05)00100-7

doi: 10.1016/j.ijoa.2005.06.007

International Journal of Obstetric Anesthesia
Volume 15, Issue 1 , Pages 41-43 , January 2006

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