International Journal of Obstetric Anesthesia
Volume 15, Issue 3 , Pages 201-205 , July 2006

A randomised double-blinded controlled trial of the effect of diluent volume on the efficacy of a single dose of epidural ropivacaine for labour analgesia

  • L. Chan
    • ,
  • B.B. Lee
    • ,
  • W.D. Ngan Kee

      Affiliations

    • Corresponding Author InformationCorrespondence to: W.D. Ngan Kee, Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China. Tel.: +852 2632 2735; fax: +852 2637 2422.

,Accepted 1 November 2005.

References 

  1. Comparative Obstetric Mobile Epidural Trial (COMET) Study Group UK . Effect of low-dose mobile versus traditional epidural techniques on mode of delivery: a randomised controlled trial. Lancet. 2001;358:19–23
  2. Christiaens F, Verborgh C, Dierick A, Camu F. Effects of diluent volume of a single dose of epidural bupivacaine in parturients during the first stage of labor. Reg Anesth Pain Med. 1998;23:134–141
  3. Lee BB, Ngan Kee WD, Wong EL, Liu JY. Dose-response study of epidural ropivacaine for labor analgesia. Anesthesiology. 2001;94:767–772
  4. Eddleston JM, Holland JJ, Griffin RP, Corbett A, Horsman EL, Reynolds F. A double-blind comparison of 0.25% ropivacaine and 0.25% bupivacaine for extradural analgesia in labour. Br J Anaesth. 1996;76:66–71
  5. Writer WDR, Stienstra R, Eddelston JM, et al. Neonatal outcome and mode of delivery after epidural analgesia for labour with ropivacaine and bupivacaine: a prospective meta-analysis. Br J Anaesth. 1998;81:713–717
  6. Muir HA, Writer D, Douglas J, Weeks S, Gambling D, Macarthur A. Double-blind comparison of epidural ropivacaine 0.25% and bupivacaine 0.25%, for the relief of childbirth pain. Can J Anaesth. 1997;44:599–604
  7. Matthews JNS, Altman DG, Campbell MJ, Royston P. Analysis of serial measurements in medical research. BMJ. 1990;300:230–235
  8. Bernard JM, Le Roux D, Frouin J. Ropivacaine and fentanyl concentrations in patient-controlled epidural analgesia during labor: a volume-range study. Anesth Analg. 2003;97:1800–1807
  9. Capogna G, Celleno D, Lyons G, Columb M, Fusco P. Minimum local analgesic concentration of extradural bupivacaine increases with progression of labour. Br J Anaesth. 1998;80:11–13
  10. Yarnell RW, Ewing DA, Tierney E, Smith MH. Sacralization of epidural block with repeated doses of 0.25% bupivacaine during labor. Reg Anesth. 1990;15:275–279

PII: S0959-289X(05)00183-4

doi: 10.1016/j.ijoa.2005.11.001

International Journal of Obstetric Anesthesia
Volume 15, Issue 3 , Pages 201-205 , July 2006

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