International Journal of Obstetric Anesthesia
Volume 17, Issue 2 , Pages 123-129 , April 2008

The incidence of maternal fever during labor is less with intermittent than with continuous epidural analgesia: a randomized controlled trial

,Accepted 1 July 2007.

References 

  1. Fusi L, Steer PJ, Maresh MJ, Beard RW. Maternal pyrexia associated with the use of epidural analgesia in labour. Lancet. 1989;1:1250–1252
  2. Lieberman E, Lang JM, Frigoletto F, Richardson DK, Ringer SA, Cohen A. Epidural analgesia, intrapartum fever, and neonatal sepsis evaluation. Pediatrics. 1997;99:415–419
  3. Kaul B, Vallejo M, Ramanathan S, Mandell G. Epidural labor analgesia and neonatal sepsis evaluation rate: a quality improvement study. Anesth Analg. 2001;93:986–990
  4. Philip J, Alexander JM, Sharma SK, Leveno KJ, McIntire DD, Wiley J. Epidural analgesia during labor and maternal fever. Anesthesiology. 1999;90:1271–1275
  5. Sharma SK, Alexander JM, Messick G, et al. Cesarean delivery: a randomized trial of epidural analgesia versus intravenous meperidine analgesia during labor in nulliparous women. Anesthesiology. 2002;96:546–551
  6. Goetzl L, Evans T, Rivers J, Suresh MS, Lieberman E. Elevated maternal and fetal serum interleukin-6 levels are associated with epidural fever. Am J Obstet Gynecol. 2002;187:834–838
  7. Ramin SM, Gambling DR, Lucas MJ, Sharma SK, Sidawi JE, Leveno KJ. Randomized trial of epidural versus intravenous analgesia during labor. Obstet Gynecol. 1995;86:783–789
  8. Glosten B, Savage M, Rooke GA, Brengelmann GL. Epidural anesthesia and the thermoregulatory responses to hyperthermia: preliminary observations in volunteer subjects. Acta Anaesthesiol Scand. 1998;42:442–446
  9. Goodlin RC, Chapin JW. Determinants of maternal temperature during labor. Am J Obstet Gynecol. 1982;143:97–103
  10. Macaulay JH, Bond K, Steer PJ. Epidural analgesia in labor and fetal hyperthermia. Obstet Gynecol. 1992;80:665–669
  11. Camann WR, Hortvet LA, Hughes N, Bader AM, Datta S. Maternal temperature regulation during extradural analgesia for labour. Br J Anaesth. 1991;67:565–568
  12. Herbst A, Wolner-Hanssen P, Ingemarsson I. Risk factors for fever in labor. Obstet Gynecol. 1995;86:790–794
  13. Smedstad KG, Morison DH. A comparative study of continuous and intermittent epidural analgesia for labour and delivery. Can J Anaesth. 1988;35:234–241
  14. Eddleston JM, Maresh M, Horsman EL, Young H, Lacey P, Anderton J. Comparison of the maternal and fetal effects associated with intermittent or continuous infusion of extradural analgesia. Br J Anaesth. 1992;69:154–158
  15. Salim R, Nachum Z, Moscovici R, Lavee M, Shalev E. Continuous compared with intermittent epidural infusion on progress of labor and patient satisfaction. Obstet Gynecol. 2005;106:301–306
  16. Wong CA, Ratliff JT, Sullivan JT, Scavone BM, Toledo P, McCarthy RJ. A randomized comparison of programmed intermittent epidural bolus with continuous epidural infusion for labor analgesia. Anesth Analg. 2006;102:904–909
  17. Vinson DC, Thomas R, Kiser T. Association between epidural analgesia during labor and fever. J Fam Pract. 1993;36:617–622
  18. Gelfand T, Palanisamy A, Tsen LC, Segal S. Warming in parturients with epidurals is an averaging artifact. SOAP abstracts 2007; A5 (http://wwwsoaporg/media/meetings/2007/SOAP_39th_Abs_Supplement_Overrunpdf).
  19. Goetzl L, Rivers J, Zighelboim I, Wali A, Badell M, Suresh MS. Intrapartum epidural analgesia and maternal temperature regulation. Obstet Gynecol. 2007;109:687–690
  20. Finegold H, Mandell G, Ramanathan S. Comparison of ropivacaine 0.1%-fentanyl and bupivacaine 0.125%-fentanyl infusions for epidural labour analgesia. Can J Anesth. 2000;47:740–745

 Source of support: Seed grant from the Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

PII: S0959-289X(07)00189-6

doi: 10.1016/j.ijoa.2007.07.006

International Journal of Obstetric Anesthesia
Volume 17, Issue 2 , Pages 123-129 , April 2008