International Journal of Obstetric Anesthesia
Volume 18, Issue 2 , Pages 150-155 , April 2009

Hetastarch co-loading is as effective as pre-loading for the prevention of hypotension following spinal anesthesia for cesarean delivery

  • B. Carvalho

      Affiliations

    • Department of Anesthesiology, Stanford University School of Medicine, California, USA
    • Corresponding Author InformationCorrespondence to: Brendan Carvalho MBBCh, FRCA, Department of Anesthesia, H3580, Stanford University School of Medicine, Stanford, California 94305. Tel.: +650 861 8607; fax: +650 725 8544.
  • ,
  • F.J. Mercier

      Affiliations

    • Department of Anesthesiology, AP-HP, A. Beclere Hospital, Clamart, France
  • ,
  • E.T. Riley

      Affiliations

    • Department of Anesthesiology, Stanford University School of Medicine, California, USA
  • ,
  • C. Brummel

      Affiliations

    • Colorado Permanente Medical Group, Lafayette, Colorado, USA
  • ,
  • S.E. Cohen

      Affiliations

    • Department of Anesthesiology, Stanford University School of Medicine, California, USA

,Accepted 8 December 2008.

References 

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  2. Morgan PJ, Halpern SH, Tarshis J. The effects of an increase of central blood volume before spinal anesthesia for cesarean delivery: a qualitative systematic review. Anesth Analg. 2001;92:997–1005
  3. Marx GF, Cosmi EV, Wollman SB. Biochemical status and clinical condition of mother and infant at cesarean section. Anesth Analg. 1969;48:986–994
  4. Corke BC, Datta S, Ostheimer GW, Weiss JB, Alper M H. Spinal anaesthesia for Caesarean section. The influence of hypotension on neonatal outcome. Anaesthesia. 1982;37:658–662
  5. Rout C, Rocke DA. Spinal hypotension associated with Cesarean section: will preload ever work? Anesthesiology. 1999;91:1565–1567
  6. Rout CC, Akoojee SS, Rocke DA, Gouws E. Rapid administration of crystalloid preload does not decrease the incidence of hypotension after spinal anaesthesia for elective caesarean section. Br J Anaesth. 1992;68:394–397
  7. Rout CC, Rocke DA, Levin J, Gouws E, Reddy D. A reevaluation of the role of crystalloid preload in the prevention of hypotension associated with spinal anesthesia for elective cesarean section. Anesthesiology. 1993;79:262–269
  8. Jackson R, Reid JA, Thorburn J. Volume preloading is not essential to prevent spinal-induced hypotension at caesarean section. Br J Anaesth. 1995;75:262–265
  9. Kamenik M, Paver-Erzen V. The effects of lactated Ringer’s solution infusion on cardiac output changes after spinal anesthesia. Anesth Analg. 2001;92:710–714
  10. Ewaldsson CA, Hahn RG. Volume kinetics of Ringer’s solution during induction of spinal and general anaesthesia. Br J Anaesth. 2001;87:406–414
  11. Dyer RA, Farina Z, Joubert IA, et al. Crystalloid preload versus rapid crystalloid administration after induction of spinal anaesthesia (coload) for elective caesarean section. Anaesth Intensive Care. 2004;32:351–357
  12. Brummel C, Mercier F, Fuller A, et al. Preloading vs. postloading of colloid for the prevention of hypotension after spinal anesthesia for cesarean section. Anesthesiology. 2004;100:A51
  13. Weeks S. Reflections on hypotension during Cesarean section under spinal anesthesia: do we need to use colloid?. Can J Anaesth. 2000;47:607–610
  14. Riley ET, Cohen SE, Rubenstein AJ, Flanagan B. Prevention of hypotension after spinal anesthesia for cesarean section: six percent hetastarch versus lactated Ringer’s solution. Anesth Analg. 1995;81:838–842
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  16. Ngan Kee WD, Khaw KS, Ng FF. Comparison of phenylephrine infusion regimens for maintaining maternal blood pressure during spinal anaesthesia for Caesarean section. Br J Anaesth. 2004;92:469–474
  17. Ngan Kee WD, Khaw KS, Ng FF. Prevention of hypotension during spinal anesthesia for cesarean delivery: an effective technique using combination phenylephrine infusion and crystalloid cohydration. Anesthesiology. 2005;103:744–750
  18. Ueyama H, He YL, Tanigami H, Mashimo T, Yoshiya I. Effects of crystalloid and colloid preload on blood volume in the parturient undergoing spinal anesthesia for elective Cesarean section. Anesthesiology. 1999;91:1571–1576
  19. Vercauteren MP, Coppejans HC, Sermeus L. Anaphylactoid reaction to hydroxyethylstarch during cesarean delivery in a patient with HELLP syndrome. Anesth Analg. 2003;96:859–861
  20. Wiedermann CJ. Hydroxyethyl starch - can the safety problems be ignored? Wien Klin Wochenschr. 2004;116:583–594
  21. Barron ME, Wilkes MM, Navickis RJ. A systematic review of the comparative safety of colloids. Arch Surg. 2004;139:552–563
  22. Butwick A, Carvalho B. The effect of colloid and crystalloid preloading on thromboelastography prior to Cesarean delivery. Can J Anaesth. 2007;54:190–195
  23. Mojica JL, Melendez HJ, Bautista LE. The timing of intravenous crystalloid administration and incidence of cardiovascular side effects during spinal anesthesia: the results from a randomized controlled trial. Anesth Analg. 2002;94:432–437
  24. Mercier FJ, Riley ET, Frederickson WL, Roger-Christoph S, Benhamou D, Cohen SE. Phenylephrine added to prophylactic ephedrine infusion during spinal anesthesia for elective cesarean section. Anesthesiology. 2001;95:668–674
  25. Lee A, Ngan Kee WD, Gin T. A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg. 2002;94:920–926
  26. Ngan Kee WD, Khaw KS. Vasopressors in obstetrics: what should we be using?. Curr Opin Anaesthesiol. 2006;19:238–243

PII: S0959-289X(09)00002-8

doi: 10.1016/j.ijoa.2008.12.006

International Journal of Obstetric Anesthesia
Volume 18, Issue 2 , Pages 150-155 , April 2009