International Journal of Obstetric Anesthesia
Volume 19, Issue 1 , Pages 16-23 , January 2010

A randomised comparison of regular oral oxycodone and intrathecal morphine for post-caesarean analgesia

  • N.J. McDonnell

      Affiliations

    • The Department of Anaesthesia and Pain Medicine, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia
    • Corresponding Author InformationCorrespondence to: Dr N McDonnell, Department of Anaesthesia and Pain Medicine, King Edward Memorial Hospital for Women, 374 Bagot Rd, Subiaco WA 6008 Australia.
    • ,
  • M.J. Paech

      Affiliations

    • School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia
    • ,
  • R.M. Browning

      Affiliations

    • The Department of Anaesthesia and Pain Medicine, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia
    • ,
  • E.A. Nathan

      Affiliations

    • Women’s and Infants Research Foundation, Perth, Western Australia, Australia

,Accepted 12 March 2009.

References 

  1. Dahl JB, Jeppesen IS, Jorgensen H, Wetterslev J, Moiniche S. Intraoperative and postoperative analgesic efficacy and adverse effects of intrathecal opioids in patients undergoing cesarean section with spinal anesthesia: a qualitative and quantitative systematic review of randomized controlled trials. Anesthesiology. 1999;91:1919–1927
  2. Cardoso MM, Carvalho JC, Amaro AR, Prado AA, Cappelli EL. Small doses of intrathecal morphine combined with systemic diclofenac for postoperative pain control after cesarean delivery. Anesth Analg. 1998;86:538–541
  3. Davis KM, Esposito MA, Meyer BA. Oral analgesia compared with intravenous patient-controlled analgesia for pain after cesarean delivery: a randomized controlled trial. Am J Obstet Gynecol. 2006;194:967–971
  4. Jakobi P, Weiner Z, Solt I, Alpert I, Itskovitz-Eldor J, Zimmer EZ. Oral analgesia in the treatment of post-cesarean pain. Eur J Obstet Gynecol Reprod Biol. 2000;93:61–64
  5. Scott S, Cameron S, Richards E. Maternal self-administration of oral analgesia after Caesarean section. Anaesthesia. 2001;56:906–924
  6. Holt M. Patient-controlled oramorph--the future?. Anaesthesia. 2000;55:933–934
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  10. Pan PH. Post cesarean delivery pain management: multimodal approach. Int J Obstet Anesth. 2006;15:185–188
  11. Lavand’homme P. Postcesarean analgesia: effective strategies and association with chronic pain. Curr Opin Anaesthesiol. 2006;19:244–248
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  14. Macintyre PE. Safety and efficacy of patient-controlled analgesia. Br J Anaesth. 2001;87:36–46
  15. Seaton S, Reeves M, McLean S. Oxycodone as a component of multimodal analgesia for lactating mothers after Caesarean section: relationships between maternal plasma, breast milk and neonatal plasma levels. Aust N Z J Obstet Gynaecol. 2007;47:181–185
  16. Riley J, Eisenberg E, Muller-Schwefe G, Drewes AM, Arendt-Nielsen L. Oxycodone: a review of its use in the management of pain. Curr Med Res Opin. 2008;24:175–192
  17. Niruthisard S, Werawataganon T, Bunburaphong P, Ussawanophakiat M, Wongsakornchaikul C, Toleb K. Improving the analgesic efficacy of intrathecal morphine with parecoxib after total abdominal hysterectomy. Anesth Analg. 2007;105:822–824
  18. Henzi I, Walder B, Tramer MR. Dexamethasone for the prevention of postoperative nausea and vomiting: a quantitative systematic review. Anesth Analg. 2000;90:186–194
  19. Wu JI, Lo Y, Chia YY, et al. Prevention of postoperative nausea and vomiting after intrathecal morphine for Cesarean section: a randomized comparison of dexamethasone, droperidol, and a combination. Int J Obstet Anesth. 2007;16:122–127
  20. Monagle J, Molnar A, Shearer W. Oral medication for post-Caesarean analgesia. Aust N Z J Obstet Gynaecol. 1998;38:169–171
  21. Jakobi P, Solt I, Tamir A, Zimmer EZ. Over-the-counter oral analgesia for postcesarean pain. Am J Obstet Gynecol. 2002;187:1066–1069
  22. Palmer CM, Emerson S, Volgoropolous D, Alves D. Dose-response relationship of intrathecal morphine for postcesarean analgesia. Anesthesiology. 1999;90:437–444
  23. Landau RG, H Fougere, B Mungier, CG Kern. Post-cesarean section analgesia: a QA survey (abstract). Anesthesiology 2003; 98(Supp 1: SOAP A38).
  24. Siddik-Sayyid SM, Aouad MT, Taha SK, et al. Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery?. Anesth Analg. 2007;104:421–424

PII: S0959-289X(09)00062-4

doi: 10.1016/j.ijoa.2009.03.004

International Journal of Obstetric Anesthesia
Volume 19, Issue 1 , Pages 16-23 , January 2010

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