Off-label use of medicines is bad medicine flying the flag of clinical freedom

References 

1. Eypasch E, Lefering R, Kum CK, Troidl H. Probability of adverse events that have not yet occurred: a statistical reminder. BMJ. 1995;311:619–620
   • MEDLINE
   • CrossRef
2. Maynard A. Translating evidence into practice: why is it so difficult?. Public Money & Management. 2007;27:251–256
3. Howell CJ. Epidural versus non-epidural analgesia for pain relief in labour. Cochrane database of systematic reviews (Online). 2000.
4. Parker M. False dichotomies: EBM, clinical freedom, and the art of medicine. J Med Ethics. 2005;31:23–30
5. Hill D. Remifentanil patient-controlled analgesia should be routinely available for use in labour: Proposer. Int J Obstet Anesth. 2008;17:336–339
   • Full Text
   • Full-Text PDF (77 KB)
   • CrossRef
6. Van de Velde M. Remifentanil patient-controlled analgesia should be routinely available for use in labour: Opposer. Int J Obstet Anesth. 2008;17:339–341
   • Full Text
   • Full-Text PDF (85 KB)
   • CrossRef
7. http://emc.medicines.org.uk/document.aspx?documentId=14766 (accessed Date 2005).
8. http://emc.medicines.org.uk/medicine/14337/XPIL/Ultiva+Injection/ (accessed Date 2008).
9. http://emc.medicines.org.uk/medicine/8375/XPIL/Diprivan+1%25/ (accessed Date 2008).
10. http://emc.medicines.org.uk/medicine/2275/SPC/Diprivan+1%25/ (accessed Date 2008).