International Journal of Obstetric Anesthesia
Volume 19, Issue 3 , Pages 293-297 , July 2010

Perineal infiltration with lidocaine 1%, ropivacaine 0.75%, or placebo for episiotomy repair in parturients who received epidural labor analgesia: a double-blind randomized study

  • N. Schinkel

      Affiliations

    • Pôle d’Anesthésie Réanimation, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • Corresponding Author InformationCorrespondence to: Naren Schinkel, M.D., Centre Hospitalo-Universitaire d’Angers, 4 rue Larrey, 49933 Angers Cedex 9, France. Tel.: +33 02 41 35 31 64; fax: +33 02 41 35 39 67.
    • ,
  • L. Colbus

      Affiliations

    • Pôle d’Anesthésie Réanimation, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • ,
  • C. Soltner

      Affiliations

    • Pôle d’Anesthésie Réanimation, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • ,
  • E. Parot-Schinkel

      Affiliations

    • Centre de Recherche Clinique, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • ,
  • L. Naar

      Affiliations

    • Pôle d’Anesthésie Réanimation, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • ,
  • A. Fournié

      Affiliations

    • Centre d’Obstétrique et de Gynécologie, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • ,
  • J.-C. Granry

      Affiliations

    • Pôle d’Anesthésie Réanimation, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France
    • ,
  • L. Beydon

      Affiliations

    • Pôle d’Anesthésie Réanimation, Centre Hospitalo-Universitaire d’Angers Angers Cedex, France

,Accepted 22 November 2009.

References 

  1. Goldberg J, Holtz D, Hyslop T, Tolosa JE. Has the use of routine episiotomy decreased? Examination of episiotomy rates from 1983 to 2000. Obstet Gynecol. 2002;99:395–400
  2. Robinson JN, Norwitz ER, Cohen AP, Lieberman E. Predictors of episiotomy use at first spontaneous vaginal delivery. Obstet Gynecol. 2000;96:214–218
  3. Vendittelli F, Gallot D. What are the epidemiologic data in regard to episiotomy?. J Gynecol Obstet Biol Reprod (Paris). 2006;35(Suppl. 1):S12–S23
  4. Cleary-Goldman J, Robinson JN. The role of episiotomy in current obstetric practice. Semin Perinatol. 2003;27:3–12
  5. Klein MC, Gauthier RJ, Robbins JM, et al. Relationship of episiotomy to perineal trauma and morbidity, sexual dysfunction, and pelvic floor relaxation. Am J Obstet Gynecol. 1994;171:591–598
  6. Macarthur AJ, Macarthur C. Incidence, severity, and determinants of perineal pain after vaginal delivery: a prospective cohort study. Am J Obstet Gynecol. 2004;191:1199–1204
  7. Khan GQ, Lilford RJ. Wound pain may be reduced by prior infiltration of the episiotomy site after delivery under epidural analgesia. Br J Obstet Gynaecol. 1987;94:341–344
  8. Verspyck E, Sentilhes L, Roman H, Sergent F, Marpeau L. Episiotomy techniques. J Gynecol Obstet Biol Reprod (Paris). 2006;35(Suppl. 1):1S40–51
  9. Vinson-Bonnet B, Coltat JC, Fingerhut A, Bonnet F. Local infiltration with ropivacaine improves immediate postoperative pain control after hemorrhoidal surgery. Dis Colon Rectum. 2002;45:104–108
  10. Pettersson N, Emanuelsson BM, Reventlid H, Hahn RG. High-dose ropivacaine wound infiltration for pain relief after inguinal hernia repair: a clinical and pharmacokinetic evaluation. Reg Anesth Pain Med. 1998;23:189–196
  11. Wulf H, Worthmann F, Behnke H, Bohle AS. Pharmacokinetics and pharmacodynamics of ropivacaine 2mg/mL, 5mg/mL, or 7.5mg/mL after ilioinguinal blockade for inguinal hernia repair in adults. Anesth Analg. 1999;89:1471–1474
  12. Aissaoui Y, Bruyère R, Mustapha H, Bry D, Drissi Kamili N, Miller C. A randomized controlled trial of pudendal nerve block for pain relief after episiotomy. Anesth Analg. 2008;107:625–629
  13. Andrews V, Thakar R, Sultan AH, Jones PW. Are mediolateral episiotomies actually mediolateral?. BJOG. 2005;112:1156–1158
  14. Quinn M. Obstetric denervation-gynaecological reinnervation: disruption of the inferior hypogastric plexus in childbirth as a source of gynaecological symptoms. Med Hypotheses. 2004;63:390–393
  15. Borg-Stein J, Dugan SA, Gruber J. Musculoskeletal aspects of pregnancy. Am J Phys Med Rehabil. 2005;84:180–192
  16. Kottenberg-Assenmacher E, Peters J. Mechanisms of tachyphylaxis in regional anesthesia of long duration. Anasthesiol Intensivmed Notfallmed Schmerzther. 1999;34:733–742
  17. Wang C, Liu H, Wilder RT, Berde CB. Effects of repeated injection of local anesthetic on sciatic nerve blocks response. J Huazhong Univ Sci Technolog Med Sci. 2004;24:497–499
  18. Wust HJ, Liebau W, Richter O, Strasser K. Achyphylaxis in der dauernden epiduralen anästhesie mit bupivacaine 0.125% und 0.25%. Anasth Intensivther Notfallmed. 1980;15:159–165
  19. Mogensen T, Simonsen L, Scott NB, Henriksen JH, Kehlet H. Tachyphylaxis associated with repeated epidural injections of lidocaine is not related to changes in distribution or the rate of elimination from the epidural space. Anesth Analg. 1989;69:180–184
  20. Guignard B, Bossard AE, Coste C, et al. Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement. Anesthesiology. 2000;93:409–417
  21. Van Elstraete AC, Sitbon P, Trabold F, Mazoit JX, Benhamou D. A single dose of intrathecal morphine in rats induces long-lasting hyperalgesia: the protective effect of prior administration of ketamine. Anesth Analg. 2005;101:1750–1756
  22. Cortinez LI, Brandes V, Munoz HR, Guerrero ME, Mur M. No clinical evidence of acute opioid tolerance after remifentanil-based anaesthesia. Br J Anaesth. 2001;87:866–869

PII: S0959-289X(09)00219-2

doi: 10.1016/j.ijoa.2009.11.005

International Journal of Obstetric Anesthesia
Volume 19, Issue 3 , Pages 293-297 , July 2010

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