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Summary
Pregnancy may occur in patients with ankylosing spondylitis, a chronic inflammatory
joint disease. This disease, which is included in the group of seronegative spondylarthropathies,
may be characterized by both intra- and extra-articular manifestations. Although most
pregnant patients with ankylosing spondylitis experience normal spontaneous vaginal
deliveries, manifestations of the disease may interfere with labor and delivery as
well as the administration of general and regional anesthesia. Therefore, physicians
caring for a pregnant patient with ankylosing spondylitis should be aware of the obstetric
and anesthetic implications and the ramifications of active disease. These patients
should be referred to an anesthesiologist early in pregnancy so that the obstetrician
and anesthesiologist can together formulate a plan.
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© 1995 Pearson Professional Ltd. Published by Elsevier Inc.