Abstract
Background
The postoperative analgesic effects of rectal indomethacin and tramadol were compared
in patients undergoing elective termination of first trimester pregnancy and diagnostic
dilatation and curettage.
Methods
Eighty-one American Society of Anesthesiologists class I and II women undergoing first
trimester termination of pregnancy or diagnostic dilation and curettage were randomly
allocated to receive rectal suppositories of either tramadol 100 mg (n = 41) or indomethacin 100 mg (n = 40) 90 min before induction of anesthesia. Pain scores and side effects were evaluated until
discharge. Intraoperative anesthetic and postoperative analgesic consumption was also
recorded. Intravenous metamizole 1 g was employed for postoperative rescue analgesia.
Results
When compared to the indomethacin group, the tramadol group required less intraoperative
propofol [136 mg ±28 vs. 160 mg ±35 (P = 0.001)], less rescue analgesia [2.4% vs. 22% (P = 0.005)] and lower visual analogue pain scores [2.4 ±8 vs. 23 ±22 (P = 0.005)]. The incidence of postoperative nausea and vomiting was similar in both groups.
Conclusion
When compared to indomethacin 100 mg, preoperative administration of tramadol 100 mg provides superior postoperative analgesia with minimal adverse effects.
Keywords
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Article info
Publication history
Published online: June 06, 2011
Accepted:
March 5,
2011
Identification
Copyright
© 2011 Published by Elsevier Inc.
