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Reducing post-caesarean delivery surgical site infections: a narrative review

  • S.E. Douville
    Affiliations
    Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia
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  • L.K. Callaway
    Affiliations
    Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia

    Department of Obstetrics and Gynaecology/Obstetric Medicine, The Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia
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  • A. Amoako
    Affiliations
    Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia

    Department of Obstetrics and Gynaecology/Obstetric Medicine, The Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia
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  • J.A. Roberts
    Affiliations
    Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia

    University of Queensland Centre for Clinical Research, The University of Queensland, Herston, Queensland, Australia

    Centre for Translational Anti-infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Herston, Queensland, Australia

    Division of Anaesthesiology Critical Care Emergency and Pain Medicine, Nîmes University Hospital, University of Montpellier, Nîmes, France

    Department of Pharmacy and Intensive Care Medicine, The Royal Brisbane and Women’s Hospital, Herston, Qld, Australia
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  • V.A. Eley
    Correspondence
    Correspondence to: V.A. Eley, Department of Anaesthesia and Perioperative Medicine, The Royal Brisbane and Women’s Hospital, Butterfield St Herston, 2006 Queensland, Australia.
    Affiliations
    Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia

    Department of Anaesthesia and Perioperative Medicine, The Royal Brisbane and Women’s Hospital, Herston, Queensland, Australia
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Published:September 05, 2019DOI:https://doi.org/10.1016/j.ijoa.2019.08.007

      Highlights

      • Reported post-caesarean surgical site infection (SSI) rates vary from 1% to 10%.
      • International variation is seen in recommended prophylactic antibiotic regimens.
      • Surgical technique for wound closure influences SSI rate.

      Abstract

      Surgical site infection complicates 1–10% of caesarean deliveries. With the rate of caesarean delivery increasing, it is important to identify effective measures of preventing surgical site infection and to consider their impact on maternal and neonatal outcomes. Compelling evidence supports the use of prophylactic antibiotics, prior to skin incision, to reduce surgical site infection. However, there remain international variations in terms of the recommended agent, dose and body weight-adjusted dosing. Advances in wound dressings are an evolving area of interest and surgical technique can influence outcomes. This narrative review explores pharmacological and non-pharmacological methods of preventing surgical site infection following caesarean delivery.

      Keywords

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