Short Report| Volume 47, 102984, August 2021

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An observational pilot study of a novel loss of resistance syringe for locating the epidural space

Published:March 26, 2021DOI:


      • EpiFaith™ is a novel loss of resistance syringe for locating the epidural space.
      • The EpiFaith™ signals when there is a loss of resistance.
      • We report on the clinical use of the EpiFaith™ loss of resistance syringe.
      • Three of four anesthesiologists rated it more highly than using their usual syringe.



      The EpiFaith® syringe is a novel loss-of-resistance syringe that utilizes a spring-loaded plunger that automatically moves forward within the syringe when there is a loss of resistance. We evaluated the syringe in a clinical setting among a cohort of pregnant women receiving neuraxial labor analgesia.


      In a non-randomized observational study, four anesthesiologists used the EpiFaith® syringe 10 times each while placing epidural catheters for labor analgesia. The anesthesiologists scored each placement on an 11-point Likert scale (−5 = absolutely worse, 0 = the same, and 5 = absolutely better than using their regular loss-of-resistance syringe technique).


      All 40 neuraxial placements correctly located the epidural space. Air was used in the syringe in 35 of the 40 cases. In 50%, 27.5% and 22.5% of cases the anesthesiologists reported that using the EpiFaith® syringe was better than, the same as, or worse than using their regular syringe, respectively. There were no inadvertent dural punctures.


      This feasibility study found that three of the four anesthesiologists scored the EpiFaith® syringe as better or the same as using their regular loss-of-resistance syringe. More extensive studies are required to determine if the EpiFaith® syringe reduces adverse outcomes such as unintentional dural punctures.


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