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Thromboelastometry guiding anesthetic and coagulation management of cesarean delivery in a parturient with factor V deficiency

Published:September 01, 2022DOI:https://doi.org/10.1016/j.ijoa.2022.103593
      Inherited Factor V (FV) deficiency is a rare but challenging bleeding disorder particularly in the context of pregnancy. A 26-year-old pregnant woman, (gravida 2, para 1) was admitted at 38 weeks’ gestation for elective cesarean delivery (CD) for obstetric reasons. The FV deficiency had been discovered during a postpartum hemorrhage (PPH) in her first pregnancy. Laboratory tests performed before the elective CD showed a prothrombin time (PT) of 23% and activated partial thromboplastin time (aPTT) of 60 s, giving a patient/control ratio of two. The FV level was 4% and other clotting factors levels were normal. The anti-FV antibody titre was negative.
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