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Effect of different crystalloid preload volumes combined with prophylactic norepinephrine infusion on inferior vena cava collapsibility index and post-spinal anesthesia hypotension during cesarean section: a randomized controlled trial

Published:September 01, 2022DOI:https://doi.org/10.1016/j.ijoa.2022.103596
      Vasopressor and fluid administration are important strategies to prevent and treat post-spinal anesthesia hypotension at cesarean section.

      Practice guidelines for obstetric anesthesia: an updated report by the American Society of Anesthesiologists Task Force on obstetric anesthesia and the Society for Obstetric Anesthesia and Perinatology. Anesthesiology 2016;124:270-300. https://doi.org/10.1097/ALN.0000000000000935.

      • Kinsella S.M.
      • Carvalho B.
      • Dyer R.A.
      • et al.
      International consensus statement on the management of hypotension with vasopressors during caesarean section under spinal anaesthesia.
      As a principal strategy, vasopressors, especially α-adrenergic agonists, are used to counteract decreases in peripheral vascular resistance induced by sympathetic blockade.
      • Ngan Kee W.D.
      • Lee S.W.Y.
      • Ng F.F.
      • et al.
      Prophylactic norepinephrine infusion for preventing hypotension during spinal anesthesia for cesarean delivery.
      The inferior vena cava (IVC) collapsibility index (CI) is a useful measure with which to estimate cardiac preload and volume status.
      • Hernandez C.A.
      • Reed K.L.
      • Juneman E.B.
      • et al.
      Changes in sonographically measured inferior vena caval diameter in response to fluid loading in term pregnancy.
      In this study we investigated the effect of different crystalloid preload volumes combined with prophylactic norepinephrine infusion on IVC-CI and post-spinal anesthesia hypotension in patients undergoing cesarean section.
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      References

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