Case Report| Volume 53, 103612, February 2023

Acute thrombocytopenia during cesarean section

  • X. Yang
    Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Xinshi District, Xinjiang Province, China
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  • Q. Xia
    Department of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Xinshi District, Xinjiang Province, China
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  • J. Wang
    Correspondence to: J. Wang, Department of Anesthesiology, The First Affiliated Hospital of Xingjiang Medical University, Xinshi District, 830000 Xinjiang province, China.
    Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Xinshi District, Xinjiang Province, China
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Published:October 28, 2022DOI:


      • Combined spinal-epidural anesthesia for elective cesarean section.
      • Heathy parturient with a normal pre-operative platelet count.
      • Acute intra-operative development of severe thrombocytopenia (3 × 109/L)
      • Likely an adverse reaction to cefoxitin given for surgical infection prophylaxis.
      • No spinal-epidural hematoma despite severe thrombocytopenia.


      We report a case of a healthy 29-year-old parturient with a normal pre-operative platelet count who received combined spinal-epidural anesthesia for cesarean section, and who suffered the sudden intra-operative onset of severe thrombocytopenia (platelet count 3 × 109/L). This event was likely due to cefoxitin administered for the prophylaxis of surgical infection.


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