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International Journal of Obstetric Anesthesia
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    • An, GH1
    • Hodsdon, A1
    • Melhuish, TM1
    • Thang, C1
    • Vlok, R1
    • White, LD1

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    • International Journal of Obstetric Anesthesia1

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    • Anaesthesia, general1
    • Opioids1
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    • Original Article

      Induction opioids for caesarean section under general anaesthesia: a systematic review and meta-analysis of randomised controlled trials

      International Journal of Obstetric Anesthesia
      Vol. 40p4–13Published online: May 14, 2019
      • L.D. White
      • A. Hodsdon
      • G.H. An
      • C. Thang
      • T.M. Melhuish
      • R. Vlok
      Cited in Scopus: 22
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        Caesarean section (CS) under general anaesthesia (GA) is commonly performed due to surgical urgency, inadequate previous block, maternal refusal or contraindication to neuraxial anaesthesia.1 The induction of general anaesthesia and initial surgical incisions cause significant sympathetic drive which may result in adverse effects, for example intracranial haemorrhage in the context of comorbidities such as pre-eclampsia.2–5 For this reason sympatholysis is often required on induction of GA and initiation of CS.
        Induction opioids for caesarean section under general anaesthesia: a systematic review and meta-analysis of randomised controlled trials
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